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7Treatment - wound closure and definitive stabilization

 A common technique is the use of antibiotic-laden polymethylmethacrylate (PMMA) beads.

Fill dead space

Antibiotic beads

Surgical débridement of unhealthy soft tissue and/or bone may leave dead space between bone ends, or under flaps.
When the excised infected wound presents “dead space”, antibiotic-laden cement is frequently used, both to fill the space and to deliver locally high doses of antibiotic. A common technique is the use of antibiotic-laden polymethylmethacrylate (PMMA) beads.